Patrick E. ‘Pat’ Hanna Obituary

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Hanna, Patrick E. “Pat” passed away peacefully in his sleep on May 4, 2022 after a five-year battle with bronchiectasis. Pat was born October 13, 1940 in Little River, Kansas and grew up in Lyons, Kansas. He was predeceased by his daughter Lori, his sister Mary Frances Riggs, his parents Henry and Pauline (Donnelly) Hanna. He is survived by his loving and devoted wife, Betty; grandson Andrew Hanna; brother Jay Hanna (Carolyn); bonus kids Shannon Borja (Donny), Susan Herzing and William Dale; bonus grandchildren Hailey and Mateo Borja, Evan and Lydia Herzing; several nieces, nephews and their children. Pat’s job in a pharmacy while in high school convinced him of the advisability of an indoor profession without heavy lifting. He entered Creighton University College of Pharmacy where he was invited to participate in a research project which stimulated his interest in chemistry and drug research. After earning her Bachelor of Science in Pharmacy, Pat earned a Doctor of Philosophy (Ph.D.) degree in Medicinal Chemistry from the University of Kansas. He immediately moved to the Twin Cities where he accepted a position at the University of Minnesota with a cross-appointment to the Department of Pharmacology at the School of Medicine and the Department of Medicinal Chemistry at the College of Pharmacy. Over the next 43 years, Pat taught extensively in the Bachelor of Science in Pharmacy and Doctor of Pharmacy programs, in the Medicinal Chemistry graduate program, and in various pharmacology and toxicology courses. He has mentored students in graduate programs in medicinal chemistry and pharmacology and served for nine years as director of graduate studies in medicinal chemistry. Pat received the Horace T. Morse-Amoco Award for Outstanding Contributions to Undergraduate Teaching in 1979. He was Distinguished Professor of Teaching at the University of Minnesota, a Fellow of the Academy of Distinguished Teachers, and a been made a Fellow of the American Association for Advancement. of Science for his educational contributions. Pat was known for sprinkling humorous commentary and stories throughout his lectures, and he sometimes pushed the envelope. Her favorite teaching review was submitted by a student who wrote “Dr. Hanna has a great sense of humor, questionable taste.” Pat’s research program has focused primarily on studies of arylamine carcinogens in tobacco smoke and in the environment. His first article on this research received the 1977 prize for the best article published in the scientific journal in which it appeared. His laboratory has made important contributions to understanding the interactions of arylamines and their metabolites with arylamine N-acetyltransferase (NAT), a key enzyme in arylamine metabolism. Research in collaboration with Professor Carston (Rick) Wagner has resulted in fundamental contributions to the understanding of the catalytic mechanism of NAT and other important aspects of NAT enzymo-logy. Pat was very proud of the many important contributions his graduate students, postdoctoral associates and professional students made to his research program. Pat was a member of several professional scientific societies. He was elected president of the Medicinal Chemistry Division of the American Chemical Society (ACS), served as an advisor to the ACS Division of Chemical Toxicology, and was associate editor of the Journal of Medicinal Chemistry for 18 years. After his retirement in 2012, Pat collaborated with Professor MW Anders as co-author of a comprehensive scientific review; the product of the five-year project was published as a 110-page article in a leading journal. Pat met Betty, the love of his life, when his daughter and son decided to introduce them. Thus began a streak of friendship, dating and love, followed by a marriage in 1986. Pat and Betty enjoyed the day hike through Minnesota state parks and northern trails Minnesota and the Arizona desert. After spending their honeymoon in Banff, they made five return visits to the Canadian Rockies. They made trips each winter to northern Minnesota for cross-country skiing and snowshoeing. They enjoyed Gopher basketball and football games and scientific trips to Australia and Europe. Two of their favorite activities were tending to their home’s wooded property and tending to their two dozen bird feeders. For many years, family gatherings have been held at their homes for Thanksgiving dinner, Christmas Eve dinner, and an outdoor Easter egg hunt. Pat and Betty enjoyed attending their grandchildren’s sporting events and other extracurricular activities and were proud of their accomplishments. Pat particularly enjoyed his time with his grandson Andrew, whom he called “the son I never had”. Pat and Betty were best friends; the more time they spent together, the stronger their bond grew. When his illness began to interfere with his physical activity, Betty became Pat’s 24-hour caregiver for over two years, using her nursing experience and love for him to provide him with the highest quality of care. possible life. Sincere thanks go to: several very special physicians from M Health Fairview, University of Minnesota Clinics, especially Drs. Vercellotti, Billings and Ryan; Allina Hospice home care staff (Ann, Sue, Kate, Sharon, Tony) and Art, a special chaplain for professional, personal and nurturing care; the caring and hardworking nurses, orderlies and therapists of Lyngblomsten Transitional Care; a volunteer visitor from Tamaris, Fred, who has become his friend; as well as colleagues and friends who visited Pat throughout his illness. In lieu of flowers, memorial donations are suggested to “The Patrick and Betty Hanna Graduate Fellowship in Medicinal Chemistry,” Fund 24126, University of Minnesota Foundation, 200 Oak Street SE, Suite 500, Minneapolis, MN 55455 or your charity prefer. A celebration of Pat’s life will be held July 10, 2022 at 2:00 p.m. at the McNamara Center at 200 Oak Street SE, Minneapolis, MN 55455.

Posted May 15, 2022

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